Randall ME, Filiaci VL, Muss H, Spirtos NM, Mannel RS, Fowler J, et al. Randomized phase III trial of whole-abdominal irradiation versus doxorubicin and cisplatin chemotherapy in advanced endometrial carcinoma: a Gynecologic Oncology Group Study. J Clin Oncol 2006 Jan 1;24(1):36-44 [Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/16330675].
Compare quality appraisals for each clinical question
- After hysterectomy, what is the role of chemotherapy (concurrent/concomitant, sequential, sandwich, chemoradiation) in the management of early stage high risk endometrial cancer?
- What is the evidence based surgical approach for lymphadenectomy in low and high risk apparent early stage endometrial cancer?