Critical appraisal:Passlick B, Kubuschock B, Sienel W, Thetter O, Pantel K, Izbicki JR 2002
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Critical Appraisal
Article being appraised
Passlick B, Kubuschock B, Sienel W, Thetter O, Pantel K, Izbicki JR. Mediastinal lymphadenectomy in non-small cell lung cancer: effectiveness in patients with or without nodal micrometastases - results of a preliminary study. Eur J Cardiothorac Surg 2002 Mar;21(3):520-6 [Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/11888774].
Applicable clinical question
Key Facts
Study Design
randomised controlled trial
Number of Patients
201
Includes an economic evaluation
no
Evidence ratings
Level of evidence
II
Quality of evidence
| High | Additional comments: Well designed RCT |
Size of effect
| 2 | Reason for decision: The point estimate of effect is clinically important, but the confidence interval includes clinically unimportant effects. |
Relevance of evidence
| 1 | Additional comments: Evidence of an effect on patient‐relevant clinical outcomes including benefits and harms, and survival. |
Result of appraisal
Included
Reason for decision
Completed by
This appraisal has been completed.- Article
- Passlick B, Kubuschock B, Sienel W, Thetter O, Pantel K, Izbicki JR. Mediastinal lymphadenectomy in non-small cell lung cancer: effectiveness in patients with or without nodal micrometastases - results of a preliminary study. Eur J Cardiothorac Surg 2002 Mar;21(3):520-6 [Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/11888774].
- Assigned to
- User:Gavin.wright
- Topic area
- Guidelines:Lung cancer/Treatment/Non-small-cell stage I operable
- Clinical question
- Clinical question:Lung cancer/Treatment/Non-small-cell stage I operable/Does complete mediastinal lymph node dissection improve overall survival compared to mediastinal lymph node staging in stage I NSCLC?
Section below only relevant for Cancer Council Project Officer
