Clinical practice guidelines for the treatment and management of endometrial cancer

Guidelines commissioned by

and developed in partnership with

Management of apparent early stage low and high risk endometrial cancer

Contents

Foreword

Summary of recommendations

(Printable version of summary of recommendations)

Multidisciplinary care

1. Is there benefit for multidisciplinary care of women with low and high-risk apparent early stage endometrial cancer?

Pre-operative investigations

1. What is the role of preoperative imaging for low and high risk apparent early stage endometrial cancer?
2. Is there a benefit to a histopathological review of currettings or biopsy prior to treatment in low and high risk apparent early stage endometrial cancer?

Surgery

1. What is the evidence based surgical approach for hysterectomy in low and high risk apparent early stage endometrial cancer?
2. What is the evidence based surgical approach for bilateral salpingo–oophorectomy in premenopausal women with low and high risk apparent early stage endometrial cancer?
3. What is the evidence based surgical approach for lymphadenectomy in low and high risk apparent early stage endometrial cancer?
4. What is the role of intra-operative assessment of the uterus in low and high risk apparent early stage endometrial cancer?

Adjuvant therapy

1. After hysterectomy, what is the role of radiotherapy (external beam, brachytherapy) in the management of early stage high risk endometrial cancer?
2. After hysterectomy, what is the role of chemotherapy (concurrent/concomitant, sequential, sandwich, chemoradiation) in the management of early stage high risk endometrial cancer?

Appendices

Guideline development process

Working party members and contributors

Conflict of interest

Further information for health professionals

Diagnostic Guide for General Practitioners and Gynaecologists

Information for consumers

Endometrial cancer consumer resources