Public comments: Premenopausal women and routine castration
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I am concerned about two issues in this chapter: 1. The issue of BSO in young patients with endometrial cancer is discussed controversially in the literature. To make a recommendation I would feel uncomforatble just disqualifying one large part of the spectrum of opinons. This issue could be solved by mentioning the diversity of evidence and clinicians may elect to preserve ovarian function in selected patients. 2. The issue of Lynch syndrome has not been discussed (?forgotten). Approximately one in five women with edometrial cancer diagnosed at or under the age of 50 years carries Lynch syndrome. These patients do not only develop bowel but also ovarian cancers. I believe that almost nobody woudl agree to retain ovaries in young females with endometrial cancer oif they tested positive for Lynch.
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Jutta von Dincklage
Project Manager - Wiki Development Cancer Council Australia
Thank you for providing comment on the draft guidelines.
The Working Party has recently met to consider all the public comments received and review the guidelines.
The following is their response to your comments above:
1. Paragraph included under Conclusion heading.
2. Lynch syndrome heading, text and recommendation included.
Manager, Cancer Guidelines Network Cancer Council Australia