Fertility preservation for AYAs diagnosed with cancer: Guidance for health professionals.

From Cancer Guidelines Wiki

Fertility preservation for AYAs diagnosed with cancer: Guidance for health professionals

This guidance has been produced by the Clinical Oncology Society of Australia (COSA) as part of a national Youth Cancer Networks Program project funded by the Australian Government.

The guidance provides evidence-based recommendations and ‘good practice points’ to assist health professionals in effectively and fully discussing with their AYA patients and their families:

  • the potential risk of cancer treatments to fertility
  • fertility preservation options for AYAs diagnosed with cancer
  • potential late effects and the need for assessment and monitoring of reproductive, sexual and endocrine health after cancer treatment ends.


Summary of recommendations (Printable version)

  1. Introduction
  2. Discussing fertility with AYAs diagnosed with cancer
  3. Managing the fertility preservation process
  4. Impact of cancer treatments on fertility
  5. Options for fertility preservation
    Oocyte and embryo freezing prior to cancer treatment
    Ovarian tissue freezing prior to cancer treatment
    Ovarian suppression with GnRH analogues during chemotherapy
    Alternative and future forms of ovarian protection
    Oophoropexy prior to pelvic irradiation
    Summary table of preservation options for female patients
    Cryopreservation of ejaculated semen (sperm banking)
    Cryopreservation of epididymal or testicular extracted sperm
    Cryopreservation of testicular tissue
  6. Long term follow up
  7. Information and support for patients and families
  8. Information and resources for health professionals

List of working group members

Public consultation

In partnership with

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