COSA:AYA cancer fertility preservation/Impact of cancer treatments on fertility/Table risk CT and RT
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Fertility preservation for AYAs diagnosed with cancer: Guidance for health professionals. > COSA:AYA cancer fertility preservation/Impact of cancer treatments on fertility/Table risk CT and RT
Table 1: Representative rates of ovarian failure after treatment of common childhood and young adult cancers *
| Disease | Likelihood of premature ovarian failure |
|---|---|
| Breast cancer (treated with chemotherapy) | |
| Age <30 years | < 10% |
| Age 30–40 years | 20 – 40% |
| Sarcoma | < 10 – 40% |
| Hodgkin lymphoma | ≥ 5% unless intensive therapy (However the risk of later onset of premature ovarian failure is 19%; average 9 years after treatment, onset of permanent ovarian failure at mean age 33.5 years) [1]
|
| non-Hodgkin lymphoma | 10 – 40% |
| Leukaemia | < 10% |
| High-dose therapy and stem-cell transplantation | > 70 – 90% |
Modified from Stern CJ, Toledo MG, Good DA, Seymour JF. Fertility preservation in female oncology patients. Aust NZ J Obstet Gynaecol 2006; 46(1): 15-23. http://www.ncbi.nlm.nih.gov/pubmed/16441687
* This table presents representative rates of ovarian failure after treatment (average >2 years after treatment), but does not consider any additional established risk of later premature ovarian failure.
References
- ↑ De Bruin ML, Huisbrink J, Hauptmann M, Kuenen MA, Ouwens GM, van't Veer MB, et al. Treatment-related risk factors for premature menopause following Hodgkin lymphoma. Blood 2008 Jan 1;111(1):101-8 Available from: http://www.ncbi.nlm.nih.gov/pubmed/17890454.