Citation:Aoyama H, Shirato H, Tago M, Nakagawa K, Toyoda T, Hatano K, et al 2006

Citation

Aoyama H, Shirato H, Tago M, Nakagawa K, Toyoda T, Hatano K, et al. Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA 2006 Jun 7;295(21):2483-91 Available from: http://www.ncbi.nlm.nih.gov/pubmed/16757720.

Critical appraisals

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Critical appraisal link	Clinical question	Assigned to	Status
Aoyama H, Shirato H, Tago M, Nakagawa K, Toyoda T, Hatano K, et al 2006	What is the role of stereotactic radiosurgery in the treatment of brain metastases?	Associate Professor Shalini Vinod MBBS MD FRANZCR	completed
Aoyama H, Shirato H, Tago M, Nakagawa K, Toyoda T, Hatano K, et al 2006 3	What is the clinical benefit of adjuvant whole brain radiotherapy following resection or stereotactic radiosurgery to the brain metastasis(es)?	Associate Professor Shalini Vinod MBBS MD FRANZCR	completed

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• [[Clinical question:What is the role of stereotactic radiosurgery in the treatment of brain metastases?|]] (compare critical appraisals)
• [[Clinical question:What is the clinical benefit of adjuvant whole brain radiotherapy following resection or stereotactic radiosurgery to the brain metastasis(es)|]] (compare critical appraisals)

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3. What is the clinical benefit of adjuvant whole brain radiotherapy following resection or stereotactic radiosurgery to the brain metastasis(es)?