Citation:Aro J, Haapiainen R, Kajanti M, Rannikko S, Alfthan O 1988 1

Citation

Aro J, Haapiainen R, Kajanti M, Rannikko S, Alfthan O. Orchiectomy, estrogen therapy and radiotherapy in locally advanced (T3-4 M0) prostatic cancer. Scand J Urol Nephrol Suppl 1988;110:103-7 Available from: http://www.ncbi.nlm.nih.gov/pubmed/3187397.

Critical appraisals

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1. What is the efficacy of external beam radiotherapy compared with other treatments for local control for locally advanced disease?
2. What should be done for patients with locally advanced disease who are not suitable candidates for surgery or radiotherapy – primary androgen deprivation at diagnosis or wait until clinical progression (localized or metastatic)?