Citation:Boccardo F, Pace M, Rubagotti A, Guarneri D, Decensi A, Oneto F, et al 1993

Citation

Boccardo F, Pace M, Rubagotti A, Guarneri D, Decensi A, Oneto F, et al. Goserelin acetate with or without flutamide in the treatment of patients with locally advanced or metastatic prostate cancer. The Italian Prostatic Cancer Project (PONCAP) Study Group. Eur J Cancer 1993;29A(8):1088-93 Available from: http://www.ncbi.nlm.nih.gov/pubmed/8518017.

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1. What should be done for patients with locally advanced disease who are not suitable candidates for surgery or radiotherapy – primary androgen deprivation at diagnosis or wait until clinical progression (localized or metastatic)?