Eggermont AMM, Blank CU, Mandala M, Long GV, Atkinson V, Dalle S, et al. Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma. N Engl J Med 2018 Apr 15 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/29658430.
Compare quality appraisals for each clinical question
- What is the appropriate treatment of macroscopic (i.e. detectable clinically or by ultrasound) nodal metastases?
- What is the role of adjuvant systemic therapy in patients with resected stage II and stage III melanoma?