Flaherty KT, Robert C, Hersey P, Nathan P, Garbe C, Milhem M, et al. Improved survival with MEK inhibition in BRAF-mutated melanoma. N Engl J Med 2012 Jul 12;367(2):107-14 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/22663011.
Compare quality appraisals for each clinical question
- Does systemic drug therapy improve progression-free, overall survival in unresectable stage III and stage IV melanoma?