Citation:Jordan WP Jr, Blackard CE, Byar DP 1977

Citation

Jordan WP Jr, Blackard CE, Byar DP. Reconsideration of orchiectomy in the treatment of advanced prostatic carcinoma. South Med J 1977 Dec;70(12):1411-3 Available from: http://www.ncbi.nlm.nih.gov/pubmed/594790.

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1. Are there differences between the different hormone therapy methods in the pattern and severity of toxicity effects for non metastatic disease?
2. Are there differences between the different hormone therapy methods in the pattern and severity of toxicity effects in metastatic disease?
3. For patients with radiologically detectable but asymptomatic disease should hormone therapy be started immediately or should it be started at the onset of symptoms?
4. What should be done for patients with locally advanced disease who are not suitable candidates for surgery or radiotherapy – primary androgen deprivation at diagnosis or wait until clinical progression (localized or metastatic) - Timing?
5. What should be done for patients with locally advanced disease who are not suitable candidates for surgery or radiotherapy – primary androgen deprivation at diagnosis or wait until clinical progression (localized or metastatic)?