Long GV, Hauschild A, Santinami M, Atkinson V, Mandalà M, Chiarion-Sileni V, et al. Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma. N Engl J Med 2017 Sep 10 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/28891408.
Compare quality appraisals for each clinical question
- Should all patients with a positive sentinel lymph node biopsy have a complete node dissection?
- What is the appropriate treatment of macroscopic (i.e. detectable clinically or by ultrasound) nodal metastases?
- What is the role of adjuvant systemic therapy in patients with resected stage II and stage III melanoma?
- When is sentinel lymph node biopsy (SLNB) indicated?