Citation:Prostate Cancer Trialists' Collaborative Group 2000
From Cancer Guidelines Wiki
Prostate Cancer Trialists' Collaborative Group. Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials. Lancet 2000 Apr 29;355(9214):1491-8 Available from: http://www.ncbi.nlm.nih.gov/pubmed/10801170.
Compare quality appraisals for each clinical question
- Is there any survival advantage for maximum androgen blockade (or combined hormone therapy) compared with single agent androgen blockade when used as first line therapy in metastatic disease?
- What should be done for patients with locally advanced disease who are not suitable candidates for surgery or radiotherapy – primary androgen deprivation at diagnosis or wait until clinical progression (localized or metastatic)?