Shepherd FA, Giaccone G, Seymour L, Debruyne C, Bezjak A, Hirsh V, et al. Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group and the European Organization for Research and Treatment of Cancer. J Clin Oncol 2002 Nov 15;20(22):4434-9 Abstract available at HTTP://WWW.NCBI.NLM.NIH.GOV/PUBMED/12431965.
Compare quality appraisals for each clinical question
- What is the optimal chemotherapy regimen and duration of therapy in extensive stage small cell lung cancer in the first line setting?
- What is the optimal systemic therapy and duration to be used for the treatment of limited stage small cell lung cancer?