Citation:Smith MR, Goode M, Zietman AL, McGovern FJ, Lee H, Finkelstein JS 2004
Smith MR, Goode M, Zietman AL, McGovern FJ, Lee H, Finkelstein JS. Bicalutamide monotherapy versus leuprolide monotherapy for prostate cancer: effects on bone mineral density and body composition. J Clin Oncol 2004 Jul 1;22(13):2546-53 Available from: http://www.ncbi.nlm.nih.gov/pubmed/15226323.
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- Are there differences between the different hormone therapy methods in the pattern and severity of toxicity effects for non metastatic disease?
- What is the incidence of osteoporosis and reduction in bone mineral density at 2, 5 and 10 years and what is the risk of osteoporotic bone fracture due to bilateral orchidectomy (or orchidectomy), LHRH agonist or long term androgen deficiency?