Steenland E, Leer JW, van Houwelingen H, Post WJ, van den Hout WB, Kievit J, et al. The effect of a single fraction compared to multiple fractions on painful bone metastases: a global analysis of the Dutch Bone Metastasis Study. Radiother Oncol 1999 Aug;52(2):101-9 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/10577695.
Compare quality appraisals for each clinical question
- What is the clinical benefit of radiotherapy to the bone for metastatic disease from NSCLC?
- What is the effectiveness of local external beam radiotherapy (EBRT) in the palliation of uncomplicated bone pain?