Clinical question comments:What is the role of early ICC/pleuradhesis or early thoracoscopic pleuradhesis in the treatment of pleural effusions in patients with stage IV inoperable NSCLC?/Recommendations

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Thread titleRepliesLast modified
Catheter Size113:55, 4 June 2012

Catheter Size

The Collaborative propose deletion of the following Recommendation: “There is a case for wider use of povidone-iodine solutions in Australia whether in the clinical or research setting.” A recommendation should be either for its use or not. There seems to be insufficient evidence to support a recommendation on this and the statement with regard to talc as the current standard for sclerotherapy should stand.

Tahlia Moss15:15, 30 May 2012

That would be doing a disservice to povidone-iodeine and ignoring the evidence around it. Outcomes in singpe arm studies are in the talc range and in one small randomised study outcomes are similar with less common severe pain than with talc. The talc recommendation should stand as carefully written but talc really only has the advantage of incumbency and familiarity of use over povidone-iodine. Where there is a reasonable body of evidence, some recommendation should emerge

Prof Matthew Peters MD FRACP13:55, 4 June 2012