Critical appraisal:1999 2

Critical Appraisal

Article being appraised

Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small-cell lung cancer. The Elderly Lung Cancer Vinorelbine Italian Study Group. J Natl Cancer Inst 1999 Jan 6;91(1):66-72 Available from: http://www.ncbi.nlm.nih.gov/pubmed/9890172.

Applicable clinical question

• What is the optimal systemic therapy regimen for patients with poor performance status for treatment of stage IV inoperable NSCLC?

Key Facts

Study Design

randomised controlled trial

Number of Patients:

191

Includes an economic evaluation

no

Evidence ratings

Level of evidence

II

Risk of bias

Moderate risk of bias

Comments: incomplete accrual

Size of effect

1	Reason for decision: Please replace this text and briefly describe the reasons for your rating

Relevance of evidence

1	Additional comments: Please replace this text and briefly describe the reasons for your rating

Result of appraisal

Included

Completed by

Assoc. Prof. Nick Pavlakis

This appraisal has been completed.

Article

Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small-cell lung cancer. The Elderly Lung Cancer Vinorelbine Italian Study Group. J Natl Cancer Inst 1999 Jan 6;91(1):66-72 Available from: http://www.ncbi.nlm.nih.gov/pubmed/9890172.

Assigned to

User:Nick.pavlakis

Topic area

Guidelines:Lung cancer

Clinical question

• What is the optimal systemic therapy regimen for patients with poor performance status for treatment of stage IV inoperable NSCLC?

Form

Form:Critical appraisal

Section below only relevant for Cancer Council Project Officer

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