Critical appraisal:Al Yami A, Griffin AM, Ferguson PC, Catton CN, Chung PW, Bell RS, et al 2010 3

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Critical Appraisal

Article being appraised

Al Yami A, Griffin AM, Ferguson PC, Catton CN, Chung PW, Bell RS, et al. Positive surgical margins in soft tissue sarcoma treated with preoperative radiation: is a postoperative boost necessary? Int J Radiat Oncol Biol Phys 2010 Jul 15;77(4):1191-7 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/20056340.


Applicable clinical question

Key Facts

Study Design

cohort study

Number of Patients:

175


Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-2

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: cohort study

Subject selection
"New technology" group
No response
Comparison group
No response
Comparability of groups on demographic characteristics and clinical features
No response
Measurement of outcomes
Outcome measures blind to technology used
No response
Same method of measurement used across comparison groups
No response
Completeness of follow-up
Was follow-up complete and were all patients included in the analysis?
No response
Size of effect
4 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
3 Additional comments: Improved local control rate seen appears largely due to pre-op radiotherapy instead of post op boost.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Julie Chu


Jutta's tick icon.png This appraisal has been completed.


Article
Al Yami A, Griffin AM, Ferguson PC, Catton CN, Chung PW, Bell RS, et al. Positive surgical margins in soft tissue sarcoma treated with preoperative radiation: is a postoperative boost necessary? Int J Radiat Oncol Biol Phys 2010 Jul 15;77(4):1191-7 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/20056340.
Assigned to
User:Marcus.foo
Topic area
Guidelines:Sarcoma
Clinical question
Form
Form:Critical appraisal


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