Critical appraisal:Alektiar KM, Hong L, Brennan MF, Della-Biancia C, Singer S 2007

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Critical Appraisal

Article being appraised

Alektiar KM, Hong L, Brennan MF, Della-Biancia C, Singer S. Intensity modulated radiation therapy for primary soft tissue sarcoma of the extremity: preliminary results. Int J Radiat Oncol Biol Phys 2007 Jun 1;68(2):458-64 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/17363186.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

31



Evidence ratings

Risk of bias assessment: case series

Subject selection:
Highly selected or not described (e.g. single-institution study)
Were the outcome measures blind to pre/post-intervention?
No or not described
Follow-up complete and all patients included in the analysis?
No or not described
Result of appraisal

Jutta's exclamation mark icon.png Excluded

Reason for decision

Main purpose of study was to report outcomes after using intensity-modulated RT. Only 7 patients were treated pre-operatively, whilst the remainder were post-operative. Only one patient relapsed locally.


Completed by

Dr Marcus Foo FRANZCR


Jutta's tick icon.png This appraisal has been completed.


Article
Alektiar KM, Hong L, Brennan MF, Della-Biancia C, Singer S. Intensity modulated radiation therapy for primary soft tissue sarcoma of the extremity: preliminary results. Int J Radiat Oncol Biol Phys 2007 Jun 1;68(2):458-64 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/17363186.
Assigned to
User:Marcus.foo
Topic area
Guidelines:Sarcoma
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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