Critical appraisal:Amichetti M, Amelio D, Cianchetti M, Enrici RM, Minniti G 2010

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Critical Appraisal

Article being appraised

Amichetti M, Amelio D, Cianchetti M, Enrici RM, Minniti G. A systematic review of proton therapy in the treatment of chondrosarcoma of the skull base. Neurosurg Rev 2010 Apr;33(2):155-65 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/19921291.


Applicable clinical question

Key Facts

Study Design

systematic review — There are no randomised studies, only case series.

Number of Patients:

Not applicable


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
Moderate risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: systematic review

Studies included in the review
Was an adequate search strategy used?
Adequate – search terms and/or choice of databases could have been improved upon
Were the inclusion criteria appropriate and applied in an unbiased way?
Adequate – inclusion criteria were pre-specified and applied by one person
Were the studies assessed for quality (relating to the minimisation of biases)?
Adequate – some problems with quality issues or assessed by one person only
Were the characteristics and results of individual studies appropriately summarised?
Adequate – more information would be desirable
The following questions are only relevant for systematic reviews that pooled data
Were the methods used for pooling the data appropriate?
Yes
If there was heterogeneity, were sources of heterogeneity explored?
Yes
Size of effect
5 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Sarat Chander FRANZCR


Jutta's tick icon.png This appraisal has been completed.


Article
Amichetti M, Amelio D, Cianchetti M, Enrici RM, Minniti G. A systematic review of proton therapy in the treatment of chondrosarcoma of the skull base. Neurosurg Rev 2010 Apr;33(2):155-65 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/19921291.
Assigned to
User:Sarat.chander
Topic area
Guidelines:Sarcoma
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment