Critical appraisal:Atean I, Pointreau Y, Rosset P, Garaud P, De-Pinieux G, Calais G 2012

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Critical Appraisal

Article being appraised

Atean I, Pointreau Y, Rosset P, Garaud P, De-Pinieux G, Calais G. Prognostic factors of extremity soft tissue sarcoma in adults. A single institutional analysis. Cancer Radiother 2012 Nov 8 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/23142179.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

87


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments: single-institution retrospective analysis

Risk of bias assessment: case series

Subject selection:
Highly selected or not described (e.g. single-institution study)
Were the outcome measures blind to pre/post-intervention?
No, but objective measures used
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Size of effect
5 Reason for decision: Not compared. p-values for prognostic factors only.
Relevance of evidence
1 Additional comments: This is a study of all patients treated with post-op RT. the main aim of the study was to examine prognostic factors, but it did report local recurrence as well as relevant survival (distant control) outcomes.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Marcus Foo FRANZCR


Jutta's tick icon.png This appraisal has been completed.


Article
Atean I, Pointreau Y, Rosset P, Garaud P, De-Pinieux G, Calais G. Prognostic factors of extremity soft tissue sarcoma in adults. A single institutional analysis. Cancer Radiother 2012 Nov 8 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/23142179.
Assigned to
User:Marcus.foo
Topic area
Guidelines:Sarcoma
Clinical question
Form
Form:Critical appraisal


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