Critical appraisal:Balamucki CJ, Mancuso AA, Amdur RJ, Kirwan JM, Morris CG, Flowers FP, et al 2012

Risk of bias assessment: cohort study

Subject selection

"New technology" group

Selected group

Comparison group

Selected group

Comparability of groups on demographic characteristics and clinical features

Not comparable and not adjusted for differences

Measurement of outcomes

Outcome measures blind to technology used

No, but objective measures used

Same method of measurement used across comparison groups

Yes

Completeness of follow-up

Was follow-up complete and were all patients included in the analysis?

Reasonable follow-up of all groups (>80%)

Overall risk of bias

High risk of bias

Additional comments:

This appraisal has been completed.

Article

Balamucki CJ, Mancuso AA, Amdur RJ, Kirwan JM, Morris CG, Flowers FP, et al. Skin carcinoma of the head and neck with perineural invasion. Am J Otolaryngol 2012 Jul;33(4):447-54 Available from: http://www.ncbi.nlm.nih.gov/pubmed/22185685.

Assigned to

User:Albert.chetcuti

Topic area

Guidelines:Keratinocyte carcinoma

Clinical question

• What should be the protocol to manage or treat locoregionally advanced cutaneous squamous cell carcinoma?

Form

Form:Quality appraisal cohort

Outcomes

Overall survival; cause-specific survival,; disease-free survival; freedom from distant metastases

Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment