Critical appraisal:Bass AJ, Meyerhardt JA, Chan JA, Giovannucci EL, Fuchs CS 2008

Risk of bias assessment: cohort study

Subject selection

"New technology" group

Selected group

Comparison group

Selected group

Comparability of groups on demographic characteristics and clinical features

Comparable

Measurement of outcomes

Outcome measures blind to technology used

No, but objective measures used

Same method of measurement used across comparison groups

Yes

Completeness of follow-up

Was follow-up complete and were all patients included in the analysis?

Yes (follow-up >95%) or survival analysis using all patients

Overall risk of bias

Moderate risk of bias

Additional comments: Please replace this text and include any additional comments in regards to your risk of bias rating

This appraisal has been completed.

Article

Bass AJ, Meyerhardt JA, Chan JA, Giovannucci EL, Fuchs CS. Family history and survival after colorectal cancer diagnosis. Cancer 2008 Mar 15;112(6):1222-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/18219663.

Assigned to

User:Ben.lee-bates

Topic area

Guidelines:Colorectal cancer

Clinical question

• FHS2: What is the strength of association between family history and colorectal cancer risk and how do these associations vary by, number of affected relatives and degree of relatedness and age and sex of affected relatives and by the age and sex of the at-risk person?

Form

Form:Quality appraisal cohort

Section below only relevant for Cancer Council Project Officer

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