Critical appraisal:Bates JE, Youn P, Usuki KY, Walter KA, Huggins CF, Okunieff P, et al 2015 2

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Risk of bias assessment: cohort study

Subject selection
"New technology" group
Selected group
Comparison group
Selected group
Comparability of groups on demographic characteristics and clinical features
Not comparable and not adjusted for differences
Measurement of outcomes
Outcome measures blind to technology used
No, but objective measures used
Same method of measurement used across comparison groups
Yes
Completeness of follow-up
Was follow-up complete and were all patients included in the analysis?
Yes (follow-up >95%) or survival analysis using all patients
Overall risk of bias
High risk of bias Additional comments: representative sample, baseline not compared, survival measures, all patients accounted for


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Article
Bates JE, Youn P, Usuki KY, Walter KA, Huggins CF, Okunieff P, et al. Brain metastasis from melanoma: the prognostic value of varying sites of extracranial disease. J Neurooncol 2015 Nov;125(2):411-8 Available from: http://www.ncbi.nlm.nih.gov/pubmed/26354772.
Assigned to
User:Cecilia.taing
Topic area
Guidelines:Melanoma
Clinical question
Form
Form:Quality appraisal cohort


Section below only relevant for Cancer Council Project Officer

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