Critical appraisal:Bell RS, O'Sullivan B, Davis A, Langer F, Cummings B, Fornasier VL 1991

From Clinical Guidelines Wiki

Critical Appraisal

Article being appraised

Bell RS, O'Sullivan B, Davis A, Langer F, Cummings B, Fornasier VL. Functional outcome in patients treated with surgery and irradiation for soft tissue tumours. J Surg Oncol 1991 Dec;48(4):224-31 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/1745046.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

88


Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-2

Risk of bias
Moderate risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: case series

Subject selection:
Selected group (e.g. multi-institution study)
Were the outcome measures blind to pre/post-intervention?
No, but objective measures used
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Size of effect
5 Reason for decision: Though no signif diff in functional outcome between preop and postop, study not designed to examine this.
Relevance of evidence
1 Additional comments: This prospective study examined functional outcomes after surgery + RT. 41/87 pts had preop RT. Though there was no sig diff in functional score between the two, because the study was not designed to examine the diff between preop vs postop, baseline characteristics between the two groups were not reported. They also report 3 local recurrences at 24mths, and survival rates consistent with other series.
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Marcus Foo FRANZCR


Jutta's tick icon.png This appraisal has been completed.


Article
Bell RS, O'Sullivan B, Davis A, Langer F, Cummings B, Fornasier VL. Functional outcome in patients treated with surgery and irradiation for soft tissue tumours. J Surg Oncol 1991 Dec;48(4):224-31 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/1745046.
Assigned to
User:Marcus.foo
Topic area
Guidelines:Sarcoma
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment