Critical appraisal:Bergeron EJ, Lin J, Chang AC, Orringer MB, Reddy RM 2014

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Critical Appraisal

Article being appraised

Bergeron EJ, Lin J, Chang AC, Orringer MB, Reddy RM. Endoscopic ultrasound is inadequate to determine which T1/T2 esophageal tumors are candidates for endoluminal therapies. J Thorac Cardiovasc Surg 2014 Feb;147(2):765-71: Discussion 771-3 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/24314788.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

107


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: case series

Subject selection:
Highly selected or not described (e.g. single-institution study)
Were the outcome measures blind to pre/post-intervention?
No, but objective measures used
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Size of effect
5 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
3 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included



Comments

This prospective single institution case series of 107 patients undergoing endoscopic ultrasound prior to oesophagectomy. Tumour depth was correctly staged by EUS in only 39% of pT1a cancers and 51% of pT1b cancers. EUS-staged cT1a-1pN0 lesions had 15% lymph node involvement of pathological specimens. Patients with pT1a-mm and pT1b lesions had lymph node spread in 9% and 17% respectively.

Completed by

Dr Jeremy Dwyer MBBS (Hons)


Jutta's tick icon.png This appraisal has been completed.


Article
Bergeron EJ, Lin J, Chang AC, Orringer MB, Reddy RM. Endoscopic ultrasound is inadequate to determine which T1/T2 esophageal tumors are candidates for endoluminal therapies. J Thorac Cardiovasc Surg 2014 Feb;147(2):765-71: Discussion 771-3 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/24314788.
Assigned to
User:Alan.moss
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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