Critical appraisal:Berrisford RG, Wong WL, Day D, Toy E, Napier M, Mitchell K, et al 2008

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Critical Appraisal

Article being appraised

Berrisford RG, Wong WL, Day D, Toy E, Napier M, Mitchell K, et al. The decision to operate: role of integrated computed tomography positron emission tomography in staging oesophageal and oesophagogastric junction cancer by the multidisciplinary team. Eur J Cardiothorac Surg 2008 Jun;33(6):1112-6 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/18328726.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

50


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: case series

Subject selection:
Highly selected or not described (e.g. single-institution study)
Were the outcome measures blind to pre/post-intervention?
No, but objective measures used
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Size of effect
5 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
2 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's exclamation mark icon.png Excluded

Reason for decision

Participants in these studies had oesophageal cancer but were not early stage.

Comments

This prospective single institution case series of 50 consecutive patients with potentially operable oesophageal or OGJ tumours showed that PET/CT re-categorised 12% of patients as inoperable on the basis of distant metastases Compared with pathological nodal status, PPV and NPV of PET/CT was 40% and 43% respectively.

Completed by

Dr Jeremy Dwyer MBBS (Hons)


Jutta's tick icon.png This appraisal has been completed.


Article
Berrisford RG, Wong WL, Day D, Toy E, Napier M, Mitchell K, et al. The decision to operate: role of integrated computed tomography positron emission tomography in staging oesophageal and oesophagogastric junction cancer by the multidisciplinary team. Eur J Cardiothorac Surg 2008 Jun;33(6):1112-6 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/18328726.
Assigned to
User:Alan.moss
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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