Critical appraisal:Berry MF, D'Amico TA, Onaitis MW, Kelsey CR 2014

Critical Appraisal

Article being appraised

Berry MF, D'Amico TA, Onaitis MW, Kelsey CR. Thoracoscopic approach to lobectomy for lung cancer does not compromise oncologic efficacy. Ann Thorac Surg 2014 Jul;98(1):197-202 Available from: http://www.ncbi.nlm.nih.gov/pubmed/24820392.

Applicable clinical question

• Is minimally invasive lobectomy as effective as open lobectomy for treatment of operable stage I NSCLC?

Key Facts

Study Design

case-control study

Study aims:

To compare survival between VATS and thoracotomy approaches to lobectomy for non-small cell lung cancer

Number of Patients:

560

Reported outcome(s):

5 year overall survival

Results of outcome(s):

5 year overall survival was similar for both groups; VATS 60.7% versus thoracotomy 54.8%, p= 0.5

Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-2

Risk of bias

High risk of bias

Comments: Please replace this text and include any additional comments in regards to your quality rating

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Risk of bias assessment: case-control study

Subject selection

Cases

Highly selected or not described (e.g. single-institution study)

Adequacy of case definition

Taken from medical records, self report without independent validation

Controls

Selected group (e.g. hospital controls)

Comparability of groups on demographic characteristics and important potential confounders

Comparable (or matched)

Ascertainment of exposure/treatment

No or not described

Follow-up complete and all patients included in the analysis?

Complete response

Size of effect

3	Reason for decision: Please replace this text and briefly describe the reasons for your rating

Relevance of evidence

1	Additional comments: Please replace this text and briefly describe the reasons for your rating

Result of appraisal

Included

Completed by

Associate Professor Gavin Wright MD FRACS PhD

This appraisal has been completed.

Article

Berry MF, D'Amico TA, Onaitis MW, Kelsey CR. Thoracoscopic approach to lobectomy for lung cancer does not compromise oncologic efficacy. Ann Thorac Surg 2014 Jul;98(1):197-202 Available from: http://www.ncbi.nlm.nih.gov/pubmed/24820392.

Assigned to

User:Gavin.wright

Topic area

Guidelines:Lung cancer/Treatment/Non-small-cell stage I operable

Clinical question

• Is minimally invasive lobectomy as effective as open lobectomy for treatment of operable stage I NSCLC?

Form

Form:Critical appraisal

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