Critical appraisal:Beydoun N, Graham PH, Browne L 2012 2

Risk of bias assessment: cohort study

Subject selection

"New technology" group

Highly selected or not described

Comparison group

Highly selected or not described

Comparability of groups on demographic characteristics and clinical features

Not comparable and not adjusted for differences

Measurement of outcomes

Outcome measures blind to technology used

No, but objective measures used

Same method of measurement used across comparison groups

Yes

Completeness of follow-up

Was follow-up complete and were all patients included in the analysis?

Yes (follow-up >95%) or survival analysis using all patients

Overall risk of bias

High risk of bias

Additional comments:

This appraisal has been completed.

Article

Beydoun N, Graham PH, Browne L. Metastatic Cutaneous Squamous Cell Carcinoma to the Axilla: A Review of Patient Outcomes and Implications for Future Practice. World J Oncol 2012 Oct;3(5):217-226 Available from: http://www.ncbi.nlm.nih.gov/pubmed/29147309.

Assigned to

User:Annika.stollery

Topic area

Guidelines:Keratinocyte carcinoma

Clinical question

• In which patients with cutaneous squamous cell carcinoma does a radiotherapy modality achieve equal or better outcomes than conventional surgery?

Form

Form:Quality appraisal cohort

Outcomes

Toxicity; Recurrence; Local control; Overall survival

Section below only relevant for Cancer Council Project Officer

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