Critical appraisal:Breyer HP, Silva De Barros SG, Maguilnik I, Edelweiss MI 2003 2

From Cancer Guidelines Wiki

Critical Appraisal

Article being appraised

Breyer HP, Silva De Barros SG, Maguilnik I, Edelweiss MI. Does methylene blue detect intestinal metaplasia in Barrett's esophagus? Gastrointest Endosc 2003 Apr;57(4):505-9 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/12665760.


Applicable clinical question

Key Facts

Study Design

case-control study

Number of Patients:

39



Evidence ratings

Level of evidence

III-2

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: case-control study

Subject selection
Cases
Highly selected or not described (e.g. single-institution study)
Adequacy of case definition
Independent validation of outcome (blind to exposure status)
Controls
From same population as cases and same exclusion criteria used
Comparability of groups on demographic characteristics and important potential confounders
Comparable (or matched)
Ascertainment of exposure/treatment
Blinded to case/control status
Follow-up complete and all patients included in the analysis?
Complete response
Size of effect
2 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
2 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Eric Y Lee BSc(Med) MBBS Hons FRACP


Jutta's tick icon.png This appraisal has been completed.


Article
Breyer HP, Silva De Barros SG, Maguilnik I, Edelweiss MI. Does methylene blue detect intestinal metaplasia in Barrett's esophagus? Gastrointest Endosc 2003 Apr;57(4):505-9 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/12665760.
Assigned to
User:Eric.lee
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment