Critical appraisal:Cameron AJ, Ott BJ, Payne WS 1985
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Critical Appraisal
Article being appraised
Cameron AJ, Ott BJ, Payne WS. The incidence of adenocarcinoma in columnar-lined (Barrett's) esophagus. N Engl J Med 1985 Oct 3;313(14):857-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/4033716.
Applicable clinical question
Key Facts
Study Design
case series
Number of Patients:
104
Includes an economic evaluation
no
Evidence ratings
Level of evidence
IV
Risk of bias
| High risk of bias | Comments: Mayo Clinic records were reviewed, and all cases that met predefined histologic criteria for the diagnosis of Barrett's esophagus in 1979 or earlier were included |
Size of effect
| 2 | Reason for decision: Provides objective data on incidence of OC post BO. |
Relevance of evidence
| 1 | Additional comments: Retrospective study with complete ascertainment. |
Result of appraisal
Included
Comments
Completed by
This appraisal has been completed.
- Article
- Cameron AJ, Ott BJ, Payne WS. The incidence of adenocarcinoma in columnar-lined (Barrett's) esophagus. N Engl J Med 1985 Oct 3;313(14):857-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/4033716.
- Assigned to
- User:Freddy.sitas
- Topic area
- Guidelines:Barrett's
- Clinical question
Section below only relevant for Cancer Council Project Officer
Complete ascertainment of cases - histological verification. The status of the remaining 104 cases was determined after a mean interval of 8.5 years. During this time, adenocarcinoma of the esophagus developed in 2 patients.