Critical appraisal:Cameron AJ, Ott BJ, Payne WS 1985
From Cancer Guidelines Wiki
Article being appraised
Cameron AJ, Ott BJ, Payne WS. The incidence of adenocarcinoma in columnar-lined (Barrett's) esophagus. N Engl J Med 1985 Oct 3;313(14):857-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/4033716.
Applicable clinical question
Number of Patients:
Includes an economic evaluation
Level of evidence
Risk of bias
|High risk of bias||Comments: Mayo Clinic records were reviewed, and all cases that met predefined histologic criteria for the diagnosis of Barrett's esophagus in 1979 or earlier were included|
Risk of bias assessment: case series
- Highly selected or not described (e.g. single-institution study)
Were the outcome measures blind to pre/post-intervention?
- No or not described
Follow-up complete and all patients included in the analysis?
- Yes (follow-up >95%)
Size of effect
|2||Reason for decision: Provides objective data on incidence of OC post BO.|
Relevance of evidence
|1||Additional comments: Retrospective study with complete ascertainment.|
Result of appraisal
Associate Professor Freddy Sitas
- Cameron AJ, Ott BJ, Payne WS. The incidence of adenocarcinoma in columnar-lined (Barrett's) esophagus. N Engl J Med 1985 Oct 3;313(14):857-9 Available from: http://www.ncbi.nlm.nih.gov/pubmed/4033716.
- Assigned to
- Topic area
- Clinical question
Section below only relevant for Cancer Council Project Officer
Complete ascertainment of cases - histological verification. The status of the remaining 104 cases was determined after a mean interval of 8.5 years. During this time, adenocarcinoma of the esophagus developed in 2 patients.