Critical appraisal:Cardozo ER, Thomson AP, Karmon AE, Dickinson KA, Wright DL, Sabatini ME 2015 2

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Critical Appraisal

Article being appraised

Cardozo ER, Thomson AP, Karmon AE, Dickinson KA, Wright DL, Sabatini ME. Ovarian stimulation and in-vitro fertilization outcomes of cancer patients undergoing fertility preservation compared to age matched controls: a 17-year experience. J Assist Reprod Genet 2015 Apr;32(4):587-96 Available from: http://www.ncbi.nlm.nih.gov/pubmed/25595540.


Applicable clinical question

Key Facts

Study Design

cohort study

Study aims:

Follow-up of all patients over a 17 year period who underwent fertility preservation treatment

Number of Patients:

63

Results of outcome(s):

Sixty-three cancer patients underwent 65 IVF cycles, and 21 returned for frozen embryo transfer. One hundred twenty-two age-matched controls underwent IVF cycles with fresh transfer, and 23 returned for frozen embryo transfer.

Includes an economic evaluation

no

Evidence ratings

Level of evidence

III-3

Risk of bias
High risk of bias Comments: All patients were followed up


Size of effect
1 Reason for decision:
Relevance of evidence
1 Additional comments: shows efficacy
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Jessica Harris

Jutta's tick icon.png This appraisal has been completed.


Article
Cardozo ER, Thomson AP, Karmon AE, Dickinson KA, Wright DL, Sabatini ME. Ovarian stimulation and in-vitro fertilization outcomes of cancer patients undergoing fertility preservation compared to age matched controls: a 17-year experience. J Assist Reprod Genet 2015 Apr;32(4):587-96 Available from: http://www.ncbi.nlm.nih.gov/pubmed/25595540.
Assigned to
User:Roger.hart
Topic area
Guidelines:COSA:Cancer fertility preservation guidelines/Options for treatment
Clinical question
Form
Form:Critical appraisal


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