Critical appraisal:Carlson CA, Kolon TF, Mattei P, Hobbie W, Gracia CR, Ogle S, et al 2017

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Critical Appraisal

Article being appraised

Carlson CA, Kolon TF, Mattei P, Hobbie W, Gracia CR, Ogle S, et al. Developing a Hospital-Wide Fertility Preservation Service for Pediatric and Young Adult Patients. J Adolesc Health 2017 Nov;61(5):571-576 Available from: http://www.ncbi.nlm.nih.gov/pubmed/28917444.


Applicable clinical question

Key Facts

Study Design

case series

Study aims:

To describe the development of a multi-disciplinary hospital wide fertility preservation service, and to assess the impact of the service with pre- and post- referral pattern analysis.

Number of Patients:

254

Patients from the Children's Hospital of Philadelphia.
Reported outcome(s):

Change in referrals to fertility team.
Description of the fertility program.

Results of outcome(s):

Post-implementation the total number of referrals to the Fertility Team increased by 70%. Referrals from outside of oncology more than doubled.
The initiative also provided opportunities for fertility related research. The fertility team gave guidance to researchers in urology, endocrine, and genetics for incorporating the use of mail-in semen analysis kits into their longitudinal studies, partnerships with haematology created opportunities for fertility preservation services as part of ongoing gene therapy.

Comments on results:

Advantages of mutlidisciplinary approach extend further than access to FP for patients, to research and collaboration.

Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments:


Size of effect
5 Reason for decision:
Relevance of evidence
1 Additional comments:
Result of appraisal

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Completed by

Yasmin Jayasinghe

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Article
Carlson CA, Kolon TF, Mattei P, Hobbie W, Gracia CR, Ogle S, et al. Developing a Hospital-Wide Fertility Preservation Service for Pediatric and Young Adult Patients. J Adolesc Health 2017 Nov;61(5):571-576 Available from: http://www.ncbi.nlm.nih.gov/pubmed/28917444.
Assigned to
User:Yasmin.jayasinghe
Topic area
Guidelines:COSA:Cancer fertility preservation guidelines/Referral to fertility specialists
Clinical question
Form
Form:Critical appraisal


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