Critical appraisal:Carrington C, Stone L, Koczwara B, Searle C, Siderov J, Stevenson B, et al 2010

From Clinical Guidelines Wiki

Critical Appraisal

Article being appraised

Carrington C, Stone L, Koczwara B, Searle C, Siderov J, Stevenson B, et al. The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy. Asia Pac J Clin Oncol 2010 Sep;6(3):220-37 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/20887505.


Applicable clinical question

Key Facts

Study Design

systematic review — mixed method

Study aims:

This guidance is intended for a multi-disciplinary audience and will have most relevance for medical,
nursing and pharmacy staff involved in the complex processes of delivering chemotherapy and associated
treatment. The scope of the guidelines includes; all patients and age groups receiving chemotherapy and
targeted therapy for the treatment of cancer and cancer therapy administered by any route in both the
hospital and home setting. These guidelines should be seen as point of reference for practitioners providing
cancer chemotherapy services.

Number of Patients:

Not applicable

Reported outcome(s):

The purpose of these guidelines is to provide recommendations on the safe prescribing, dispensing and administration of chemotherapy and related agents used in the treatment of cancer. The aim is to assist in the prevention of medication errors and to improve patient safety with respect to the treatment of cancer. These are
consensus guidelines based on the best available evidence and expert opinion of professionals working in cancer care. It is intended that these guidelines be used as a tool to inform local practice and adapted locally
according to service provision, applicability and availability
of resources. Whilst their purpose is to guide
clinical practice these guidelines do not replace clinician
judgment.

Results of outcome(s):

These guidelines provide recommendations on the safe prescribing, dispensing and administration of
chemotherapy and related agents used in the treatment of cancer. The guidelines represent a multidisciplinary
collaboration to standardise the complex process of providing chemotherapy for cancer and to
enhance patient safety. These are consensus guidelines based on the best available evidence and expert
opinion of professionals working in cancer care. The aim of these guidelines is to assist in the prevention of
medication errors and to improve patient safety with respect to the treatment of cancer.

Comments on results:

This guidance is intended for a multi-disciplinary audience and will have most relevance for medical,
nursing and pharmacy staff involved in the complex processes of delivering chemotherapy and associated
treatment. The scope of the guidelines includes; all patients and age groups receiving chemotherapy and
targeted therapy for the treatment of cancer and cancer therapy administered by any route in both the
hospital and home setting. These guidelines should be seen as point of reference for practitioners providing
cancer chemotherapy services.

Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
Low risk of bias Comments: Please replace this text and include any additional comments in regards to your risk of bias rating

Risk of bias assessment: systematic review

Studies included in the review
Was an adequate search strategy used?
Adequate – search terms and/or choice of databases could have been improved upon
Were the inclusion criteria appropriate and applied in an unbiased way?
Adequate – inclusion criteria were pre-specified and applied by one person
Were the studies assessed for quality (relating to the minimisation of biases)?
Yes – appropriate quality issues were assessed independently by two people
Were the characteristics and results of individual studies appropriately summarised?
Yes – summary descriptive tables of subjects, interventions, outcomes etc are provided and estimates of treatment effect displayed
The following questions are only relevant for systematic reviews that pooled data
Were the methods used for pooling the data appropriate?
No pooling
If there was heterogeneity, were sources of heterogeneity explored?
No pooling


Relevance of evidence
2 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included



Comments

Original guidelines

Completed by

Christine Carrington


Jutta's tick icon.png This appraisal has been completed.


Article
Carrington C, Stone L, Koczwara B, Searle C, Siderov J, Stevenson B, et al. The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy. Asia Pac J Clin Oncol 2010 Sep;6(3):220-37 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/20887505.
Assigned to
User:Christine.carrington
Topic area
Guidelines:
Property "Appraisal topic" (as page type) with input value "Guidelines:" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment