Chemaly M, Scalone O, Durivage G, Napoleon B, Pujol B, Lefort C, et al. Miniprobe EUS in the pretherapeutic assessment of early esophageal neoplasia. Endoscopy 2008 Jan;40(1):2-6 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/18058614.
|High risk of bias||Comments: This is a single-centre case series of 106 superficial and naive esophageal lesions (52 adenocarcinoma, 54 SCC).|
Risk of bias assessment: case series
- Highly selected or not described (e.g. single-institution study)
- No, but objective measures used
- Yes (follow-up >95%)
|5||Reason for decision: Please replace this text and briefly describe the reasons for your rating|
|3||Additional comments: This study reported on test accuracy but not on outcomes.|
Study was not exclusively of patients with adenocarcinoma (i.e. included SCC).
This retrospective, single-centre case series of 106 superficial oesophageal cancers (52 adenocarcinomas, 54 SCC) found that the overall accuracy, sensitivity, and specificity to differentiate T1sm from T1 m tumors were 73.5 %, 62 %, and 76.5 %, respectively. Overdiagnosis occurred in 18.6 % of the lesions. No statistically significant difference was found in the accuracy of the miniprobe staging between the two lesion types (SCC and adenocarcinoma), and results were significantly poorer in the distal part of the oesophagus. The authors concluded that high-frequency miniprobe examination has a limited accuracy in the detection of submucosal invasion in early oesophageal cancer.
- Chemaly M, Scalone O, Durivage G, Napoleon B, Pujol B, Lefort C, et al. Miniprobe EUS in the pretherapeutic assessment of early esophageal neoplasia. Endoscopy 2008 Jan;40(1):2-6 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/18058614.
- Assigned to
- Topic area
- Clinical question
Section below only relevant for Cancer Council Project Officer