Critical appraisal:Cobo A, García-Velasco J, Domingo J, Pellicer A, Remohí J 2018
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Critical Appraisal
Article being appraised
Cobo A, García-Velasco J, Domingo J, Pellicer A, Remohí J. Elective and Onco-fertility preservation: factors related to IVF outcomes. Hum Reprod 2018 Dec 1;33(12):2222-2231 Available from: http://www.ncbi.nlm.nih.gov/pubmed/30383235.
Applicable clinical question
Key Facts
Study Design
cohort study
Number of Patients:
1073
Results of outcome(s):
Ongoing pregnancy (57.7% vs. 35.7%) and live birth rates (68.8% vs. 41.1%) were higher
in EFP patients aged ≤35 than the Onco-FP matching age patients (P < 0.05).
Comments on results:
Statistical power to compare IVF outcomes is limited by the few women who came to use
their oocytes in the Onco-FP group. The patients’ ages and the COS protocols used were significantly different between the EFP and
ONCO-PP groups.
Includes an economic evaluation
no
Evidence ratings
Level of evidence
III-3
Risk of bias
| High risk of bias | Comments: |
Result of appraisal
Included
This appraisal has been completed.
- Article
- Cobo A, García-Velasco J, Domingo J, Pellicer A, Remohí J. Elective and Onco-fertility preservation: factors related to IVF outcomes. Hum Reprod 2018 Dec 1;33(12):2222-2231 Available from: http://www.ncbi.nlm.nih.gov/pubmed/30383235.
- Assigned to
- User:jessica.harris
- Topic area
- Guidelines:COSA:Cancer fertility preservation guidelines/Options for treatment
- Clinical question
Section below only relevant for Cancer Council Project Officer