Critical appraisal:Cook NR, Lee IM, Zhang SM, Moorthy MV, Buring JE 2013 2

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Jutta's tick icon.png This appraisal has been completed.


Article
Cook NR, Lee IM, Zhang SM, Moorthy MV, Buring JE. Alternate-day, low-dose aspirin and cancer risk: long-term observational follow-up of a randomized trial. Ann Intern Med 2013 Jul 16;159(2):77-85 Available from: http://www.ncbi.nlm.nih.gov/pubmed/23856681.
Assigned to
User:Albert.chetcuti
Topic area
Guidelines:Colorectal cancer
Clinical question
Form
Form:Critical appraisal
Outcomes
Adverse effects
Study design
randomised controlled trial - Cochrane tool
Clinical trial
WHS

Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment


Critical Appraisal

Article being appraised

Cook NR, Lee IM, Zhang SM, Moorthy MV, Buring JE. Alternate-day, low-dose aspirin and cancer risk: long-term observational follow-up of a randomized trial. Ann Intern Med 2013 Jul 16;159(2):77-85 Available from: http://www.ncbi.nlm.nih.gov/pubmed/23856681.


Applicable clinical question

Key Facts

Study Design

randomised controlled trial

Number of Patients:

Not applicable


Includes an economic evaluation

no

Evidence ratings

Level of evidence

I

Risk of bias
Low risk of bias Comments: Please replace this text and include any additional comments in regards to your risk of bias rating

Risk of bias assessment: randomised controlled trial

Was the trial double-blinded?
No response
Was the treatment allocation schedule concealed?
No response
Were all randomised participants included in the analysis?
No response
The field below is not considered when calculating the risk of bias rating
How was the allocation schedule generated?
No response
Size of effect
1 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
1 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Albert Chetcuti BTech(Biotech) Hons, PhD

Risk of bias assessment: randomised controlled trial

Was the trial double-blinded?
No response
Was the treatment allocation schedule concealed?
No response
Were all randomised participants included in the analysis?
No response
The field below is not considered when calculating the risk of bias rating
How was the allocation schedule generated?
No response