Critical appraisal:Corkum KS, Rhee DS, Wafford QE, Demeestere I, Dasgupta R, Baertschiger R, et al 2019

From Cancer Guidelines Wiki

Critical Appraisal

Article being appraised

Corkum KS, Rhee DS, Wafford QE, Demeestere I, Dasgupta R, Baertschiger R, et al. Fertility and hormone preservation and restoration for female children and adolescents receiving gonadotoxic cancer treatments: A systematic review. J Pediatr Surg 2019 Jan 22 Available from: http://www.ncbi.nlm.nih.gov/pubmed/30773394.


Applicable clinical question

Key Facts

Study Design

systematic review

Number of Patients:

18

18 patients had grafting

1019 patients had cryopreservation

37 patients had transposition



Evidence ratings

Level of evidence

IV

Risk of bias
Low risk of bias Comments:


Size of effect
5 Reason for decision:
Relevance of evidence
1 Additional comments: in adults good evidence

in paediatric patients only 3 reports of livebirth
restoration of hormone function also documented

Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Jessica Harris

Jutta's tick icon.png This appraisal has been completed.


Article
Corkum KS, Rhee DS, Wafford QE, Demeestere I, Dasgupta R, Baertschiger R, et al. Fertility and hormone preservation and restoration for female children and adolescents receiving gonadotoxic cancer treatments: A systematic review. J Pediatr Surg 2019 Jan 22 Available from: http://www.ncbi.nlm.nih.gov/pubmed/30773394.
Assigned to
User:Kate.stern
Topic area
Guidelines:COSA:Cancer fertility preservation guidelines/Options for treatment
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment