Critical appraisal:Delbaldo C, Michiels S, Syz N, Soria JC, Le Chevalier T, Pignon JP 2004 5

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Critical Appraisal

Article being appraised

Delbaldo C, Michiels S, Syz N, Soria JC, Le Chevalier T, Pignon JP. Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: a meta-analysis. JAMA 2004 Jul 28;292(4):470-84 Available from: http://www.ncbi.nlm.nih.gov/pubmed/15280345.


Applicable clinical question

Key Facts

Study Design

systematic review — randomized controlled trials

Number of Patients:

13601


Includes an economic evaluation

no

Evidence ratings

Level of evidence

I

Risk of bias
Low risk of bias Comments:


Size of effect
1 Reason for decision:
Relevance of evidence
1 Additional comments:
Result of appraisal

Jutta's exclamation mark icon.png Excluded

Reason for decision

This is the same work as the Cochrane review from 2007 that I have included and there is no point including both.


Completed by

Mustafa Khasraw MBChB MD MRCP FRACP


Jutta's tick icon.png This appraisal has been completed.


Article
Delbaldo C, Michiels S, Syz N, Soria JC, Le Chevalier T, Pignon JP. Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: a meta-analysis. JAMA 2004 Jul 28;292(4):470-84 Available from: http://www.ncbi.nlm.nih.gov/pubmed/15280345.
Assigned to
User:Nick.pavlakis
Topic area
Guidelines:Lung cancer
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

Edit appraisal assignment