Critical appraisal:Desai TK, Krishnan K, Samala N, Singh J, Cluley J, Perla S, et al 2012

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Critical Appraisal

Article being appraised

Desai TK, Krishnan K, Samala N, Singh J, Cluley J, Perla S, et al. The incidence of oesophageal adenocarcinoma in non-dysplastic Barrett's oesophagus: a meta-analysis. Gut 2012 Jul;61(7):970-6 Available from: http://www.ncbi.nlm.nih.gov/pubmed/21997553.


Applicable clinical question

Key Facts

Study Design

prevalence and incidence study

Number of Patients:

Not applicable



Evidence ratings

Risk of bias
Moderate risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: prevalence and incidence study

Source population of patients
Selected group (multiple institutions)
Subject (sample) selection
Representative of eligible patients (consecutive or random sample e.g. states all patients recruited in given time frame)
Measurement of condition
Objective and reliable (based on registry or other equivalent source)
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Result of appraisal

Jutta's tick icon.png Included



Comments

Meta analysis of 57/3450 papers. 11434 patients with BO included. 58547 PY. Ann incidence of OAC 0.33 % (0.28-0.38), 1 in 300.

Completed by

Associate Professor Freddy Sitas


Jutta's tick icon.png This appraisal has been completed.


Article
Desai TK, Krishnan K, Samala N, Singh J, Cluley J, Perla S, et al. The incidence of oesophageal adenocarcinoma in non-dysplastic Barrett's oesophagus: a meta-analysis. Gut 2012 Jul;61(7):970-6 Available from: http://www.ncbi.nlm.nih.gov/pubmed/21997553.
Assigned to
User:Freddy.sitas
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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