Critical appraisal:Dolmans MM, Jadoul P, Gilliaux S, Amorim CA, Luyckx V, Squifflet J, et al 2013

Critical Appraisal

Article being appraised

Dolmans MM, Jadoul P, Gilliaux S, Amorim CA, Luyckx V, Squifflet J, et al. A review of 15 years of ovarian tissue bank activities. J Assist Reprod Genet 2013 Mar;30(3):305-14 Available from: http://www.ncbi.nlm.nih.gov/pubmed/23417329.

Applicable clinical question

• In female cancer patients does ovarian tissue cryopreservation result in pregnancy and livebirth? Is there any reduction in the quality of oocytes/follicles? Can transplantation restore pubertal development? Are there any risks involved?

Key Facts

Study Design

case series

Study aims:

summarise data from 15 yrs but will have info relating to prevalence of cancer cells in tissue

Number of Patients:

11

582 OTC
11 grafts

Reported outcome(s):

tissue results

Results of outcome(s):

can see in abstract

Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias

High risk of bias

Comments:

Size of effect

5	Reason for decision:

Relevance of evidence

1	Additional comments:

Result of appraisal

Included

Completed by

Dr Jessica Harris

This appraisal has been completed.

Article

Dolmans MM, Jadoul P, Gilliaux S, Amorim CA, Luyckx V, Squifflet J, et al. A review of 15 years of ovarian tissue bank activities. J Assist Reprod Genet 2013 Mar;30(3):305-14 Available from: http://www.ncbi.nlm.nih.gov/pubmed/23417329.

Assigned to

User:Kate.stern

Topic area

Guidelines:COSA:Cancer fertility preservation guidelines/Options for treatment

Clinical question

• In female cancer patients does ovarian tissue cryopreservation result in pregnancy and livebirth? Is there any reduction in the quality of oocytes/follicles? Can transplantation restore pubertal development? Are there any risks involved?

Form

Form:Critical appraisal

Section below only relevant for Cancer Council Project Officer

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