Critical appraisal:Fernández-Sordo JO, Konda VJ, Chennat J, Madrigal-Hoyos E, Posner MC, Ferguson MK, et al 2012

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Critical Appraisal

Article being appraised

Fernández-Sordo JO, Konda VJ, Chennat J, Madrigal-Hoyos E, Posner MC, Ferguson MK, et al. Is Endoscopic Ultrasound (EUS) necessary in the pre-therapeutic assessment of Barrett's esophagus with early neoplasia? J Gastrointest Oncol 2012 Dec;3(4):314-21 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/23205307.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

109


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: case series

Subject selection:
Highly selected or not described (e.g. single-institution study)
Were the outcome measures blind to pre/post-intervention?
No, but objective measures used
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Size of effect
5 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
3 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included



Comments

In this retrospective, single-institution case series of 109 patients, EUS assessment was classified as suspicious for invasion in 19 patients; 84% of them had no evidence of invasion in final pathology. The authors concluded that the assessment of depth of invasion of Barrett’s neoplasia based solely on EUS findings leads to overstaging in most patients.

Completed by

Dr Jeremy Dwyer MBBS (Hons)


Jutta's tick icon.png This appraisal has been completed.


Article
Fernández-Sordo JO, Konda VJ, Chennat J, Madrigal-Hoyos E, Posner MC, Ferguson MK, et al. Is Endoscopic Ultrasound (EUS) necessary in the pre-therapeutic assessment of Barrett's esophagus with early neoplasia? J Gastrointest Oncol 2012 Dec;3(4):314-21 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/23205307.
Assigned to
User:Alan.moss
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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