Critical appraisal:Fong Y, Coit DG, Woodruff JM, Brennan MF 1993

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Critical Appraisal

Article being appraised

Fong Y, Coit DG, Woodruff JM, Brennan MF. Lymph node metastasis from soft tissue sarcoma in adults. Analysis of data from a prospective database of 1772 sarcoma patients. Ann Surg 1993 Jan;217(1):72-7 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/8424704.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

46


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
Low risk of bias Comments: Historical case series of lymph node mets in adult soft tissue sarcoma, from MSKCC over 10 yrs 1982-1991.

46/1772 LN mets, path subtype: Embryonal RMS 12/88(14%), non-embryonal RMS 1/35 (3%) Angiosarc 5/37 (14%) Epithelioid 2/12 (17%) Lymphangiosarc 1/4 (25%) no clear cell sarc otherwise <5%

Risk of bias assessment: case series

Subject selection:
Representative of eligible patients (e.g. population-based cancer registry)
Were the outcome measures blind to pre/post-intervention?
Yes
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Size of effect
2 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
1 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Roger Woods MBBS, FRACS


Jutta's tick icon.png This appraisal has been completed.


Article
Fong Y, Coit DG, Woodruff JM, Brennan MF. Lymph node metastasis from soft tissue sarcoma in adults. Analysis of data from a prospective database of 1772 sarcoma patients. Ann Surg 1993 Jan;217(1):72-7 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/8424704.
Assigned to
User:Roger.woods
Topic area
Guidelines:Sarcoma/AYA
Clinical question
Form
Form:Critical appraisal


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