Critical appraisal:Galey KM, Wilshire CL, Watson TJ, Schneider MD, Kaul V, Jones CE, et al 2011

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Critical Appraisal

Article being appraised

Galey KM, Wilshire CL, Watson TJ, Schneider MD, Kaul V, Jones CE, et al. Endoscopic management of early esophageal neoplasia: an emerging standard. J Gastrointest Surg 2011 Oct;15(10):1728-35 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/21811883.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

11


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments: Small study but well conducted and with quite good follow-up data. other studies are larger but this seems more complete and followup longer.

Risk of bias assessment: case series

Subject selection:
Highly selected or not described (e.g. single-institution study)
Were the outcome measures blind to pre/post-intervention?
No, but objective measures used
Follow-up complete and all patients included in the analysis?
Yes (follow-up >95%)
Size of effect
5 Reason for decision: too small to do stats
Relevance of evidence
2 Additional comments: evidence of effect of surrogate (LGD)
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Andrew Taylor MBBS MD FRACP


Jutta's tick icon.png This appraisal has been completed.


Article
Galey KM, Wilshire CL, Watson TJ, Schneider MD, Kaul V, Jones CE, et al. Endoscopic management of early esophageal neoplasia: an emerging standard. J Gastrointest Surg 2011 Oct;15(10):1728-35 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/21811883.
Assigned to
User:Andrew.taylor
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


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