Critical appraisal:Gatenby PA, Caygill CP, Ramus JR, Charlett A, Fitzgerald RC, Watson A 2007
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Critical Appraisal
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Gatenby PA, Caygill CP, Ramus JR, Charlett A, Fitzgerald RC, Watson A. Short segment columnar-lined oesophagus: an underestimated cancer risk? A large cohort study of the relationship between Barrett's columnar-lined oesophagus segment length and adenocarcinoma risk. Eur J Gastroenterol Hepatol 2007 Nov;19(11):969-75 Available from: http://www.ncbi.nlm.nih.gov/pubmed/18049166.
Applicable clinical question
Key Facts
Study Design
prevalence and incidence study
Number of Patients:
781
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| Moderate risk of bias | Comments: Please replace this text and include any additional comments in regards to your quality rating |
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- Article
- Gatenby PA, Caygill CP, Ramus JR, Charlett A, Fitzgerald RC, Watson A. Short segment columnar-lined oesophagus: an underestimated cancer risk? A large cohort study of the relationship between Barrett's columnar-lined oesophagus segment length and adenocarcinoma risk. Eur J Gastroenterol Hepatol 2007 Nov;19(11):969-75 Available from: http://www.ncbi.nlm.nih.gov/pubmed/18049166.
- Assigned to
- User:Freddy.sitas
- Topic area
- Guidelines:Barrett's
- Clinical question
Section below only relevant for Cancer Council Project Officer
UK National Barrett’s Oesophagus Registry (UKBOR). The overall annual adenocarcinoma incidence
was 0.62%/year (95% confidence interval: 0.36–1.01). The annual incidence in the segment length groups was 0.59% (0.19–1.37) in short segment (r3 cm), 0.099% (0.025–0.55) in > 3 r6 cm, 0.98% (0.27–2.52) in >6 r9 cm and 2.0% (0.73–4.35) in > 9 cm; P = 0.004.