Critical appraisal:Gonzalez S, Yu WM, Smith MS, Slack KN, Rotterdam H, Abrams JA, et al 2010

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Critical Appraisal

Article being appraised

Gonzalez S, Yu WM, Smith MS, Slack KN, Rotterdam H, Abrams JA, et al. Randomized comparison of 3 different-sized biopsy forceps for quality of sampling in Barrett's esophagus. Gastrointest Endosc 2010 Nov;72(5):935-40 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/21034895.


Applicable clinical question

Key Facts

Study Design

randomised controlled trial

Number of Patients:

65



Evidence ratings

Level of evidence

II

Risk of bias
Moderate risk of bias Comments: Please replace this text and include any additional comments in regards to your quality rating

Risk of bias assessment: randomised controlled trial

Was the trial double-blinded?
Trial was double-blinded but may have limitations (eg method of blinding inappropriate, tablet vs injection with no double-dummy, different treatment schedules, side-effects may unblind)

or
single-blinded (eg outcomes assessed blind, objective outcomes, no revealing side-effects).

Was the treatment allocation schedule concealed?
Inadequately concealed (e.g. numbered/sealed envelopes, alternation, medical record number, date of birth).
Were all randomised participants included in the analysis?
No exclusions or survival analysis used with all subjects included (>95% follow-up for all groups).
The field below is not considered when calculating the risk of bias rating
How was the allocation schedule generated?
Adequate (e.g. random number table, computer random generator, coin tossing, card shuffling)
Size of effect
2 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
2 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Eric Y Lee BSc(Med) MBBS Hons FRACP


Jutta's tick icon.png This appraisal has been completed.


Article
Gonzalez S, Yu WM, Smith MS, Slack KN, Rotterdam H, Abrams JA, et al. Randomized comparison of 3 different-sized biopsy forceps for quality of sampling in Barrett's esophagus. Gastrointest Endosc 2010 Nov;72(5):935-40 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/21034895.
Assigned to
User:Eric.lee
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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