Critical appraisal:Gow KW, Rapkin LB, Olson TA, Durham MM, Wyly B, Shehata BM 2008

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Critical Appraisal

Article being appraised

Gow KW, Rapkin LB, Olson TA, Durham MM, Wyly B, Shehata BM. Sentinel lymph node biopsy in the pediatric population. J Pediatr Surg 2008 Dec;43(12):2193-8 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/19040933.


Applicable clinical question

Key Facts

Study Design

case series

Number of Patients:

10


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments: Small case series of paediatric sarcoma patients undergoing SNBx (10 with sarcoma, 10 other; path subtypes 5 synovial, 3 alveolar RMS, 1 epithelioid, 1 other).1/10 positive in patient with alveolar SNBx

Safe and effective, but no comment on complications/side effects Justifies use if >10% risk of LN mets

Risk of bias assessment: case series

Subject selection:
Highly selected or not described (e.g. single-institution study)
Were the outcome measures blind to pre/post-intervention?
Yes
Follow-up complete and all patients included in the analysis?
Reasonable (follow-up >80%)
Size of effect
2 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
2 Additional comments: Please replace this text and briefly describe the reasons for your rating
Result of appraisal

Jutta's tick icon.png Included




Completed by

Dr Roger Woods MBBS, FRACS


Jutta's tick icon.png This appraisal has been completed.


Article
Gow KW, Rapkin LB, Olson TA, Durham MM, Wyly B, Shehata BM. Sentinel lymph node biopsy in the pediatric population. J Pediatr Surg 2008 Dec;43(12):2193-8 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/19040933.
Assigned to
User:Roger.woods
Topic area
Guidelines:Guidelines:Sarcoma/AYA/Sentinel lymph nose biopsy
Clinical question
Form
Form:Critical appraisal


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