Critical appraisal:Green S, Tawil A, Barr H, Bennett C, Bhandari P, Decaestecker J, et al 2009

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Critical Appraisal

Article being appraised

Green S, Tawil A, Barr H, Bennett C, Bhandari P, Decaestecker J, et al. Surgery versus radical endotherapies for early cancer and high grade dysplasia in Barrett's oesophagus. Cochrane Database Syst Rev 2009 Apr 15;(2):CD007334 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/19370683.


Applicable clinical question

Key Facts

Study Design

systematic review — no suitable RCT found so none included

Number of Patients:

0


Includes an economic evaluation

no

Evidence ratings

Level of evidence

IV

Risk of bias
High risk of bias Comments: 12 studies excluded no rct comparing management in HGD/intramucosal cnacer

Risk of bias assessment: systematic review

Studies included in the review
Was an adequate search strategy used?
Very thorough – included appropriate search terms and databases
Were the inclusion criteria appropriate and applied in an unbiased way?
Yes – pre-specified inclusion criteria applied independently by two people
Were the studies assessed for quality (relating to the minimisation of biases)?
Yes – appropriate quality issues were assessed independently by two people
Were the characteristics and results of individual studies appropriately summarised?
No
The following questions are only relevant for systematic reviews that pooled data
Were the methods used for pooling the data appropriate?
No response
If there was heterogeneity, were sources of heterogeneity explored?
No response
Size of effect
5 Reason for decision: Please replace this text and briefly describe the reasons for your rating
Relevance of evidence
6 Additional comments: no evidence to apply
Result of appraisal

Jutta's tick icon.png Included




Completed by

Associate Professor Bernard Mark Smithers


Jutta's tick icon.png This appraisal has been completed.


Article
Green S, Tawil A, Barr H, Bennett C, Bhandari P, Decaestecker J, et al. Surgery versus radical endotherapies for early cancer and high grade dysplasia in Barrett's oesophagus. Cochrane Database Syst Rev 2009 Apr 15;(2):CD007334 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/19370683.
Assigned to
User:Bernard.smithers
Topic area
Guidelines:Barrett's
Clinical question
Form
Form:Critical appraisal


Section below only relevant for Cancer Council Project Officer

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